Vitamin D and Effective Mechanisms in the Control of Body Weight

Abstract

Recently, hypovitaminosis D and obesity have reached large masses worldwide simultaneously. The number of studies linking two public health problems is increasing day by day. Vitamin D deficiency and related disorders are among the leading problems. A stronger perspective is that vitamin D deficiency causes obesity. Obesity is becoming a rapidly increasing health problem today. Particularly, studies have shown that obese individuals are at risk for Vitamin D deficiency and that increasing Body Mass Index leads to a decrease in Vitamin D levels. It is known that adipocyte tissue stores soluble vitamin D. Vitamin D affects the growth and differentiation of adipose tissue through different mechanisms.  It could lead to many factors such as changes in leptin-ghrelin levels, parathyroid hormone level, calcium level, vitamin D accumulation in adipose tissue to these mechanisms. Various studies have been conducted to understand the link between abdominal obesity and blood levels of vitamin D3. Waist circumference, which is an important indicator of fat accumulation in the abdominal area, is significantly affected by the level of vitamin D3. In addition, regular vitamin D intake also affects the release of Leptin and Ghrelin. This study aims to examine vitamin D and its effective mechanisms in body weight control, the roles of vitamin D on adipocyte cells, the relationship of hormones such as ghrelin and leptin with vitamin D and their relationship with fat oxidation.